Spermidine Rejuvenates Oocyte Quality by Enhancing Mitophagy During Female Reproductive Aging
Aging is a key risk factor for infertility in individuals with ovaries due to a decrease in ovarian reserve and egg quality. The significance of metabolic processes in reproductive aging remains unclear. Our study used untargeted metabolomics and identified spermidine as an essential metabolite that protects eggs from aging. We observed lower levels of spermidine […]